Posted on October 20, 2012 by
+ Author Affiliations
From the Department of Psychological Medicine (K.M.S.), Dunedin School of Medicine, University of Otago, Dunedin; and Department of Psychological Medicine (D.A.R.S., P.M.E.), University of Otago, Wellington, New Zealand.
- Address correspondence and reprint requests to Kate M. Scott, PhD, Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand. E-mail: email@example.com
Objective Despite growing evidence from longitudinal studies of a link between early-life stress and the development of asthma, very few of these examine one of the most severe types of early-life stress: childhood maltreatment. Cross-sectional studies on this topic have relied on retrospective self-reports of maltreatment. This study investigates associations between childhood maltreatment indicated by child protection agency records versus self-reports and lifetime asthma diagnosis in young adults, adjusting for socioeconomic status and mental disorders.
Methods A nationally representative general population survey of DSM-IV mental disorders in New Zealand (n = 12,992) obtained information on lifetime diagnoses of chronic physical conditions. Information from a subsample of survey respondents aged 16 to 27 years (n = 1413) was linked with a national child protection database to identify respondents with a history of agency involvement, which was used as a proxy for childhood maltreatment. Retrospective reports of maltreatment were also obtained.
Results Child protection agency history was associated with elevated odds (odds ratio = 2.88 [95% confidence interval = 1.7?4.74]) of a lifetime diagnosis of asthma. After adjusting for a variety of indicators of socioeconomic status, lifetime mental disorders, lifetime smoking, and body mass index, this association remained significantly elevated (odds ratio = 2.26 [95% confidence interval = 1.33?3.83]). Retrospectively self-reported maltreatment in childhood was not associated with asthma.
Conclusions Childhood maltreatment was associated with elevated odds of asthma diagnosis. These findings are consistent with the possibility that early-life stress may be one of the environmental factors that increase the risk of asthma in genetically vulnerable individuals.
- confidence interval
- Received November 9, 2011.
- Revision received June 5, 2012.
- Copyright ? 2012 by the American Psychosomatic Society