Posted on January 16, 2013 by
Mult Scler. 2011 Nov;17(11):1387-9. doi: 10.1177/1352458511410344. Epub 2011 Jun 7.
Delayed fingolimod-associated asystole.
Espinosa PS, Berger JR.
North Oaks Neurology, Hammond, LA, USA. email@example.com
Oral fingolimod (Gilenya) is a sphingosine-1-phosphate-receptor modulator that prevents the egress of lymphocytes from lymph nodes. Fingolimod reduces relapses and delays disability progression in patients with relapsing forms of multiple sclerosis (MS). We report a patient with MS who developed asystole and sustained bradycardia 21 hours after the first dose of fingolimod.
[PubMed – indexed for MEDLINE]
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